Barrett’s to Oesophageal Cancer Sequence: A Model of Inflammatory-Driven Upper Gastrointestinal Cancer

Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer.

Cancer-related inflammation is considered the 'seventh hallmark of cancer'; many studies show that tumours develop and progress within inflammatory diseases. This review focuses on Barrett's oesophagus, a common condition in which chronic inflammation and resulting alterations in the stroma can lead to carcinogenesis, specifically oesophageal adenocarcinoma. Changes that occur in the tissue mic...

Aorto-oesophageal fistula with upper gastrointestinal tract intramural haematoma in an oesophageal cancer patient.

Sudden onset haematemesis occurred in a 52-year old male with oesophageal cancer. Computed tomography showed an aorto-oesophageal fistula with contrast extravasation from the aorta. Thoracic endovascular aortic repair with stent graft was done. The haematemesis stopped postoperatively, but follow-up images (Fig. 1) showed persistent contrast extravasation. The patient died of another episode of...

Prognostic factors of survival of patients with oesophageal cancer under radiotherapy using cox regression model

oesophageal cancer is one of the most fatal cancer in human in spite of high incidence in the north of Iran and poor prognosis,there is not information regarding prognostic factors in this area.this study was conducted to determine prognodtic factors of the survival of patients with oesophageal cancer under radiotherapy.We conducted a descriptive-analytical study using historical cohort that ha...

Cancer of the upper gastrointestinal tract.

GASTROINTESTINAL CANCER Predictive value of alarm features in a rapid access upper gastrointestinal cancer service

Aims: (i) To determine the value of individual alarm features for predicting cancer in subjects referred to a rapid access upper gastrointestinal cancer service; and (ii) to develop a clinical prediction model for cancer and to prospectively validate this model in a further patient cohort. Methods: Patient demographics, referral indications, and subsequent diagnosis were recorded prospectively....